Neuroleptic malignant syndrome (NMS) which can result in Dying. Show you Health care provider immediately Should you have any of the next indicators of NMS: higher fever

eleven)]. Observe patients for indications of urinary retention or minimized gastric motility when promethazine HCl and codeine phosphate oral solution is utilized concomitantly with anticholinergic medications.

If this SPL incorporates inactivated NDCs mentioned with the FDA initiated compliance motion, they will be specified as a result.

Asthma and various Pulmonary Sickness The usage of promethazine HCl and codeine phosphate oral Remedy in clients with acute or serious bronchial bronchial asthma within an unmonitored placing or during the absence of resuscitative equipment is contraindicated [see Contraindications (four)]. Opioid analgesics and antitussives, such as codeine, one of many Lively ingredients in promethazine HCl and codeine phosphate oral Answer, should not be Employed in individuals with acute febrile disease related to successful cough or in patients with chronic respiratory illness exactly where interference with capacity to very clear the tracheobronchial tree of secretions would've a deleterious effect on the client’s respiratory functionality.

Do not consider any benzodiazepines or medicines that might cause drowsiness or sleepiness for the duration of therapy with Promethazine Hydrochloride and Codeine Phosphate Oral Option. Question your Health care supplier for a list of these medicines if You're not sure.

Due to the fact these reactions may be noted voluntarily from a population of unsure dimensions, It isn't often doable to reliably estimate their frequency or create a causal relationship to drug exposure.

Reproductive toxicity scientific tests have not been conducted with promethazine HCl and codeine phosphate oral solution; having said that, scientific studies are offered with personal active substances (see Facts).

If concomitant use is warranted, meticulously observe the affected individual, especially during treatment method initiation. Discontinue promethazine HCl and codeine phosphate oral Option if serotonin syndrome is suspected.

In certain Females, this happens very quickly. Codeine and morphine go into your breast milk. A great deal of morphine could potentially cause your baby to die.

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Promethazine HCl and codeine phosphate oral Alternative is just not advised for use in pregnant Gals. Prolonged usage of promethazine HCl and codeine phosphate oral Answer throughout pregnancy may end up in neonatal opioid withdrawal syndrome, which may be lifetime-threatening if not regarded and treated.

It is soluble in h2o and freely soluble in Alcoholic beverages. The molecular excess weight is 320.88. Its molecular method is C17H20N2S•HCl, and it's the next chemical composition.

Lower hypertension. A unexpected drop in hypertension can transpire in a number of people through procedure with Promethazine Hydrochloride and Codeine Phosphate Oral Resolution which may result in you to come to feel dizzy, faint, lightheaded, or weak, particularly when you get up (orthostatic hypotension). Your possibility of getting this issue might be amplified if you're taking read more Promethazine Hydrochloride and Codeine Phosphate Oral Alternative with specific other medicines that reduced blood pressure level.

Never just take any benzodiazepines or medicines that can result in drowsiness or sleepiness for the duration of treatment with Promethazine Hydrochloride and Codeine Phosphate Oral Solution. Check with your Health care provider for a summary of these medicines if You're not sure.